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SPOT-Contact-LM: improving single-sequence-based prediction of protein contact map using a transformer language model

MOTIVATION: Accurate prediction of protein contact-map is essential for accurate protein structure and function prediction. As a result, many methods have been developed for protein contact map prediction. However, most methods rely on protein-sequence-evolutionary information, which may not exist f...

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Detalles Bibliográficos
Autores principales: Singh, Jaspreet, Litfin, Thomas, Singh, Jaswinder, Paliwal, Kuldip, Zhou, Yaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113311/
https://www.ncbi.nlm.nih.gov/pubmed/35104320
http://dx.doi.org/10.1093/bioinformatics/btac053

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