TopHap: rapid inference of key phylogenetic structures from common haplotypes in large genome collections with limited diversity

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MOTIVATION: Building reliable phylogenies from very large collections of sequences with a limited number of phylogenetically informative sites is challenging because sequencing errors and recurrent/backward mutations interfere with the phylogenetic signal, confounding true evolutionary relationships...

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Detalles Bibliográficos
Autores principales: Caraballo-Ortiz, Marcos A, Miura, Sayaka, Sanderford, Maxwell, Dolker, Tenzin, Tao, Qiqing, Weaver, Steven, Pond, Sergei L K, Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113349/
https://www.ncbi.nlm.nih.gov/pubmed/35561179
http://dx.doi.org/10.1093/bioinformatics/btac186

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