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Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants

BACKGROUND: Neutralizing antibodies are approved drugs to treat coronavirus disease-2019 (COVID-19) patients, yet mutations in severe acute respiratory syndrome coronavirus (SARS-CoV-2) variants may reduce the antibody neutralizing activity. New monoclonal antibodies (mAbs) and antibody remolding st...

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Detalles Bibliográficos
Autores principales:	Li, Lili, Gao, Meiling, Jiao, Peng, Zu, Shulong, Deng, Yong-qiang, Wan, Dingyi, Cao, Yang, Duan, Jing, Aliyari, Saba R, Li, Jie, Shi, Yueyue, Rao, Zihe, Qin, Cheng-feng, Guo, Yu, Cheng, Genhong, Yang, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113379/ https://www.ncbi.nlm.nih.gov/pubmed/35581593 http://dx.doi.org/10.1186/s13578-022-00794-7

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