Discovery of novel secondary metabolites encoded in actinomycete genomes through coculture

Actinomycetes are a rich source of bioactive natural products important for novel drug leads. Recent genome mining approaches have revealed an enormous number of secondary metabolite biosynthetic gene clusters (smBGCs) in actinomycetes. However, under standard laboratory culture conditions, many smB...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hun, Lee, Namil, Hwang, Soonkyu, Kim, Woori, Lee, Yongjae, Cho, Suhyung, Palsson, Bernhard O, Cho, Byung-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Natural Products
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113425/
https://www.ncbi.nlm.nih.gov/pubmed/33825906
http://dx.doi.org/10.1093/jimb/kuaa001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113425/
https://www.ncbi.nlm.nih.gov/pubmed/33825906
http://dx.doi.org/10.1093/jimb/kuaa001

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