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Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes

Mutational processes in tumors create distinctive patterns of mutations, composed of neutral “passenger” mutations and oncogenic drivers that have quantifiable effects on the proliferation and survival of cancer cell lineages. Increases in proliferation and survival are mediated by natural selection...

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Detalles Bibliográficos
Autores principales: Cannataro, Vincent L., Mandell, Jeffrey D., Townsend, Jeffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113445/
https://www.ncbi.nlm.nih.gov/pubmed/35580068
http://dx.doi.org/10.1093/molbev/msac084