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Attribution of Cancer Origins to Endogenous, Exogenous, and Preventable Mutational Processes
Mutational processes in tumors create distinctive patterns of mutations, composed of neutral “passenger” mutations and oncogenic drivers that have quantifiable effects on the proliferation and survival of cancer cell lineages. Increases in proliferation and survival are mediated by natural selection...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113445/ https://www.ncbi.nlm.nih.gov/pubmed/35580068 http://dx.doi.org/10.1093/molbev/msac084 |