Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome

We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients’ specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of...

Descripción completa

Detalles Bibliográficos
Autores principales: Szydłowicz, Magdalena, Królak-Olejnik, Barbara, Vargas, Sergio L, Zajączkowska, Żaneta, Paluszyńska, Dorota, Szczygieł, Anna, Matos, Olga, Hendrich, Andrzej B, Kicia, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113508/
https://www.ncbi.nlm.nih.gov/pubmed/33857302
http://dx.doi.org/10.1093/infdis/jiab209
_version_ 1784709597373661184
author Szydłowicz, Magdalena
Królak-Olejnik, Barbara
Vargas, Sergio L
Zajączkowska, Żaneta
Paluszyńska, Dorota
Szczygieł, Anna
Matos, Olga
Hendrich, Andrzej B
Kicia, Marta
author_facet Szydłowicz, Magdalena
Królak-Olejnik, Barbara
Vargas, Sergio L
Zajączkowska, Żaneta
Paluszyńska, Dorota
Szczygieł, Anna
Matos, Olga
Hendrich, Andrzej B
Kicia, Marta
author_sort Szydłowicz, Magdalena
collection PubMed
description We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients’ specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development.
format Online
Article
Text
id pubmed-9113508
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-91135082022-05-18 Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome Szydłowicz, Magdalena Królak-Olejnik, Barbara Vargas, Sergio L Zajączkowska, Żaneta Paluszyńska, Dorota Szczygieł, Anna Matos, Olga Hendrich, Andrzej B Kicia, Marta J Infect Dis Major Articles and Brief Reports We describe the prevalence of Pneumocystis jirovecii in mother-infant pairs of very low birth weight newborns <32 weeks gestation. Molecular and microscopic methods were used for detection of P. jirovecii in patients’ specimens. Pneumocystis DNA was detected in 8 nasopharyngeal aspirates (14%) of 56 newborns and in 7 oral washes (21%) of 34 mothers. Pneumocystis detection immediately after birth suggests the possibility of its transplacental transmission. Compared to noncolonized infants, more frequent occurrence of bronchopulmonary dysplasia was seen in colonized infants (P = .02), suggesting a potential clinical importance of this pathogen in abnormal lung development. Oxford University Press 2021-04-15 /pmc/articles/PMC9113508/ /pubmed/33857302 http://dx.doi.org/10.1093/infdis/jiab209 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Major Articles and Brief Reports
Szydłowicz, Magdalena
Królak-Olejnik, Barbara
Vargas, Sergio L
Zajączkowska, Żaneta
Paluszyńska, Dorota
Szczygieł, Anna
Matos, Olga
Hendrich, Andrzej B
Kicia, Marta
Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
title Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
title_full Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
title_fullStr Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
title_full_unstemmed Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
title_short Pneumocystis jirovecii Colonization in Preterm Newborns With Respiratory Distress Syndrome
title_sort pneumocystis jirovecii colonization in preterm newborns with respiratory distress syndrome
topic Major Articles and Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113508/
https://www.ncbi.nlm.nih.gov/pubmed/33857302
http://dx.doi.org/10.1093/infdis/jiab209
work_keys_str_mv AT szydłowiczmagdalena pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT krolakolejnikbarbara pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT vargassergiol pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT zajaczkowskazaneta pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT paluszynskadorota pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT szczygiełanna pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT matosolga pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT hendrichandrzejb pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome
AT kiciamarta pneumocystisjiroveciicolonizationinpretermnewbornswithrespiratorydistresssyndrome

Ejemplares similares