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ITGBL1 transcriptionally inhibited by JDP2 promotes the development of pancreatic cancer through the TGF-beta/Smad pathway

Pancreatic cancer (PC) is one of the malignant tumors with the worst prognosis worldwide because of a lack of early diagnostic markers and efficient therapies. Integrin, beta-like 1 (ITGBL1) is a β-integrin-related extracellular matrix protein and is reported to promote progression of some types of...

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Detalles Bibliográficos
Autores principales: Du, Tiancong, Zhang, Ke, Zhang, Zhongbo, Guo, Aijia, Yu, Guilin, Xu, Yuanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113530/
https://www.ncbi.nlm.nih.gov/pubmed/35584452
http://dx.doi.org/10.1590/1414-431X2022e11989