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An evolutionary conserved detoxification system for membrane lipid–derived peroxyl radicals in Gram-negative bacteria
How double-membraned Gram-negative bacteria overcome lipid peroxidation is virtually unknown. Bactericidal antibiotics and superoxide ion stress stimulate the transcription of the Burkholderia cenocepacia bcnA gene that encodes a secreted lipocalin. bcnA gene orthologs are conserved in bacteria and...
Autores principales: | Naguib, Marwa, Feldman, Nicolás, Zarodkiewicz, Paulina, Shropshire, Holly, Biamis, Christina, El-Halfawy, Omar M., McCain, Julia, Dezanet, Clément, Décout, Jean-Luc, Chen, Yin, Cosa, Gonzalo, Valvano, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113575/ https://www.ncbi.nlm.nih.gov/pubmed/35580139 http://dx.doi.org/10.1371/journal.pbio.3001610 |
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