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An evolutionary conserved detoxification system for membrane lipid–derived peroxyl radicals in Gram-negative bacteria

How double-membraned Gram-negative bacteria overcome lipid peroxidation is virtually unknown. Bactericidal antibiotics and superoxide ion stress stimulate the transcription of the Burkholderia cenocepacia bcnA gene that encodes a secreted lipocalin. bcnA gene orthologs are conserved in bacteria and...

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Detalles Bibliográficos
Autores principales: Naguib, Marwa, Feldman, Nicolás, Zarodkiewicz, Paulina, Shropshire, Holly, Biamis, Christina, El-Halfawy, Omar M., McCain, Julia, Dezanet, Clément, Décout, Jean-Luc, Chen, Yin, Cosa, Gonzalo, Valvano, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113575/
https://www.ncbi.nlm.nih.gov/pubmed/35580139
http://dx.doi.org/10.1371/journal.pbio.3001610

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