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Snapshots of actin and tubulin folding inside the TRiC chaperonin
The integrity of a cell’s proteome depends on correct folding of polypeptides by chaperonins. The chaperonin TCP-1 ring complex (TRiC) acts as obligate folder for >10% of cytosolic proteins, including he cytoskeletal proteins actin and tubulin. Although its architecture and how it recognizes fold...
Autores principales: | Kelly, John J., Tranter, Dale, Pardon, Els, Chi, Gamma, Kramer, Holger, Happonen, Lotta, Knee, Kelly M., Janz, Jay M., Steyaert, Jan, Bulawa, Christine, Paavilainen, Ville O., Huiskonen, Juha T., Yue, Wyatt W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113939/ https://www.ncbi.nlm.nih.gov/pubmed/35449234 http://dx.doi.org/10.1038/s41594-022-00755-1 |
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