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Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response

Hikeshi mediates the nuclear import of the molecular chaperone HSP70 under heat-shock (acute heat stress) conditions, which is crucial for recovery from cellular damage. The cytoplasmic function of HSP70 is well studied, but its nuclear roles, particularly under nonstressed conditions, remain obscur...

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Detalles Bibliográficos
Autores principales:	Kose, Shingo, Imai, Kenichiro, Watanabe, Ai, Nakai, Akira, Suzuki, Yutaka, Imamoto, Naoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113944/ https://www.ncbi.nlm.nih.gov/pubmed/35580988 http://dx.doi.org/10.26508/lsa.202101241

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