Fra-2 overexpression upregulates pro-metastatic cell-adhesion molecules, promotes pulmonary metastasis, and reduces survival in a spontaneous xenograft model of human breast cancer

PURPOSE: The transcription factor Fra-2 affects the invasive potential of breast cancer cells by dysregulating adhesion molecules in vitro. Previous results suggested that it upregulates the expression of E- and P-selectin ligands. Such selectin ligands are important members of the leukocyte adhesio...

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Detalles Bibliográficos
Autores principales: Arnold, Sabrina, Kortland, Jan, Maltseva, Diana V., Nersisyan, Stepan A., Samatov, Timur R., Lezius, Susanne, Tonevitsky, Alexander G., Milde-Langosch, Karin, Wicklein, Daniel, Schumacher, Udo, Stürken, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114065/
https://www.ncbi.nlm.nih.gov/pubmed/34693476
http://dx.doi.org/10.1007/s00432-021-03812-2

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