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CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate
CUX2 gene encodes a transcription factor that controls neuronal proliferation, dendrite branching and synapse formation, locating at the epilepsy-associated chromosomal region 12q24 that we previously identified by a genome-wide association study (GWAS) in Japanese population. A CUX2 recurrent de no...
Autores principales: | Suzuki, Toshimitsu, Tatsukawa, Tetsuya, Sudo, Genki, Delandre, Caroline, Pai, Yun Jin, Miyamoto, Hiroyuki, Raveau, Matthieu, Shimohata, Atsushi, Ohmori, Iori, Hamano, Shin-ichiro, Haginoya, Kazuhiro, Uematsu, Mitsugu, Takahashi, Yukitoshi, Morimoto, Masafumi, Fujimoto, Shinji, Osaka, Hitoshi, Oguni, Hirokazu, Osawa, Makiko, Ishii, Atsushi, Hirose, Shinichi, Kaneko, Sunao, Inoue, Yushi, Moore, Adrian Walton, Yamakawa, Kazuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114133/ https://www.ncbi.nlm.nih.gov/pubmed/35581205 http://dx.doi.org/10.1038/s41598-022-10715-w |
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