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Periodic recurrent waves of Covid-19 epidemics and vaccination campaign

While understanding of periodic recurrent waves of Covid-19 epidemics would aid to combat the pandemics, quantitative analysis of data over a two years period from the outbreak, is lacking. The complexity of Covid-19 recurrent waves is related with the concurrent role of i) the containment measures...

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Detalles Bibliográficos
Autores principales: Campi, Gaetano, Bianconi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114150/
https://www.ncbi.nlm.nih.gov/pubmed/35601116
http://dx.doi.org/10.1016/j.chaos.2022.112216
Descripción
Sumario:While understanding of periodic recurrent waves of Covid-19 epidemics would aid to combat the pandemics, quantitative analysis of data over a two years period from the outbreak, is lacking. The complexity of Covid-19 recurrent waves is related with the concurrent role of i) the containment measures enforced to mitigate the epidemics spreading ii) the rate of viral gene mutations, and iii) the variable immune response of the host implemented by vaccination. This work focuses on the effect of massive vaccination and gene variants on the recurrent waves in a representative case of countries enforcing mitigation and vaccination strategy. The spreading rate is measured by the ratio between the reproductive number R(t)(t) and the doubling time T(d)(t) called RIC-index and the daily fatalities number. The dynamics of the Covid-19 epidemics have been studied by wavelet analysis and represented by a non-linear helicoid vortex in a 3D space where both RIC-index and fatalities change with time. The onset of periodic recurrent waves has been identified by the transition from convergent to divergent trajectories on the helicoid vortex. We report a main period of recurrent waves of 120 days and the elongation of this period after the vaccination campaign.