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Periodic recurrent waves of Covid-19 epidemics and vaccination campaign

While understanding of periodic recurrent waves of Covid-19 epidemics would aid to combat the pandemics, quantitative analysis of data over a two years period from the outbreak, is lacking. The complexity of Covid-19 recurrent waves is related with the concurrent role of i) the containment measures...

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Autores principales: Campi, Gaetano, Bianconi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114150/
https://www.ncbi.nlm.nih.gov/pubmed/35601116
http://dx.doi.org/10.1016/j.chaos.2022.112216
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author Campi, Gaetano
Bianconi, Antonio
author_facet Campi, Gaetano
Bianconi, Antonio
author_sort Campi, Gaetano
collection PubMed
description While understanding of periodic recurrent waves of Covid-19 epidemics would aid to combat the pandemics, quantitative analysis of data over a two years period from the outbreak, is lacking. The complexity of Covid-19 recurrent waves is related with the concurrent role of i) the containment measures enforced to mitigate the epidemics spreading ii) the rate of viral gene mutations, and iii) the variable immune response of the host implemented by vaccination. This work focuses on the effect of massive vaccination and gene variants on the recurrent waves in a representative case of countries enforcing mitigation and vaccination strategy. The spreading rate is measured by the ratio between the reproductive number R(t)(t) and the doubling time T(d)(t) called RIC-index and the daily fatalities number. The dynamics of the Covid-19 epidemics have been studied by wavelet analysis and represented by a non-linear helicoid vortex in a 3D space where both RIC-index and fatalities change with time. The onset of periodic recurrent waves has been identified by the transition from convergent to divergent trajectories on the helicoid vortex. We report a main period of recurrent waves of 120 days and the elongation of this period after the vaccination campaign.
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spelling pubmed-91141502022-05-18 Periodic recurrent waves of Covid-19 epidemics and vaccination campaign Campi, Gaetano Bianconi, Antonio Chaos Solitons Fractals Article While understanding of periodic recurrent waves of Covid-19 epidemics would aid to combat the pandemics, quantitative analysis of data over a two years period from the outbreak, is lacking. The complexity of Covid-19 recurrent waves is related with the concurrent role of i) the containment measures enforced to mitigate the epidemics spreading ii) the rate of viral gene mutations, and iii) the variable immune response of the host implemented by vaccination. This work focuses on the effect of massive vaccination and gene variants on the recurrent waves in a representative case of countries enforcing mitigation and vaccination strategy. The spreading rate is measured by the ratio between the reproductive number R(t)(t) and the doubling time T(d)(t) called RIC-index and the daily fatalities number. The dynamics of the Covid-19 epidemics have been studied by wavelet analysis and represented by a non-linear helicoid vortex in a 3D space where both RIC-index and fatalities change with time. The onset of periodic recurrent waves has been identified by the transition from convergent to divergent trajectories on the helicoid vortex. We report a main period of recurrent waves of 120 days and the elongation of this period after the vaccination campaign. Elsevier Ltd. 2022-07 2022-05-18 /pmc/articles/PMC9114150/ /pubmed/35601116 http://dx.doi.org/10.1016/j.chaos.2022.112216 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Campi, Gaetano
Bianconi, Antonio
Periodic recurrent waves of Covid-19 epidemics and vaccination campaign
title Periodic recurrent waves of Covid-19 epidemics and vaccination campaign
title_full Periodic recurrent waves of Covid-19 epidemics and vaccination campaign
title_fullStr Periodic recurrent waves of Covid-19 epidemics and vaccination campaign
title_full_unstemmed Periodic recurrent waves of Covid-19 epidemics and vaccination campaign
title_short Periodic recurrent waves of Covid-19 epidemics and vaccination campaign
title_sort periodic recurrent waves of covid-19 epidemics and vaccination campaign
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114150/
https://www.ncbi.nlm.nih.gov/pubmed/35601116
http://dx.doi.org/10.1016/j.chaos.2022.112216
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