Redirecting anti-Vaccinia virus T cell immunity for cancer treatment by AAV-mediated delivery of the VV B8R gene

Immunotherapies, such as immune checkpoint inhibitors (ICIs) and chimeric antigen receptor-T (CAR-T) cells, are only efficient in a small proportion of tumor patients. One of the major reasons for this is the lack of immune cell infiltration and activation in the tumor microenvironment (TME). Recent...

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Detalles Bibliográficos
Autores principales: Cao, Dujuan, Song, Qianqian, Li, Junqi, Chard Dunmall, Louisa S., Jiang, Yuanyuan, Qin, Bin, Wang, Jianyao, Guo, Haoran, Cheng, Zhenguo, Wang, Zhimin, Lemoine, Nicholas R., Lu, Shuangshuang, Wang, Yaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114156/
https://www.ncbi.nlm.nih.gov/pubmed/35615262
http://dx.doi.org/10.1016/j.omto.2022.04.008

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