MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report()

Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a new type of autoimmune astrocytopathy first defined in 2016. Lack of clinical understanding, often misdiagnosed as optic neuromyelitis or multiple sclerosis. We report the clinical and MRI findings of an elderly patient with aut...

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Detalles Bibliográficos
Autores principales: Ma, Wenhui, Huang, Cong, Yang, Lu, Luo, Junde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114157/
https://www.ncbi.nlm.nih.gov/pubmed/35601378
http://dx.doi.org/10.1016/j.radcr.2022.04.032
Descripción
Sumario:Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a new type of autoimmune astrocytopathy first defined in 2016. Lack of clinical understanding, often misdiagnosed as optic neuromyelitis or multiple sclerosis. We report the clinical and MRI findings of an elderly patient with autoimmune glial fibrillary acidic protein astrocytopathy. With intractable vomiting as the first symptom, the brainstem showed typical vascular enhancement. GFAP-A lacks specificity in clinical and MRI scans. When enhancement reveals paraventricular “vascular-like enhancement” or central spinal cord tubular enhancement, it is important to consider the possibility of this disease.

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