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MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report()
Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a new type of autoimmune astrocytopathy first defined in 2016. Lack of clinical understanding, often misdiagnosed as optic neuromyelitis or multiple sclerosis. We report the clinical and MRI findings of an elderly patient with aut...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114157/ https://www.ncbi.nlm.nih.gov/pubmed/35601378 http://dx.doi.org/10.1016/j.radcr.2022.04.032 |
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author | Ma, Wenhui Huang, Cong Yang, Lu Luo, Junde |
author_facet | Ma, Wenhui Huang, Cong Yang, Lu Luo, Junde |
author_sort | Ma, Wenhui |
collection | PubMed |
description | Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a new type of autoimmune astrocytopathy first defined in 2016. Lack of clinical understanding, often misdiagnosed as optic neuromyelitis or multiple sclerosis. We report the clinical and MRI findings of an elderly patient with autoimmune glial fibrillary acidic protein astrocytopathy. With intractable vomiting as the first symptom, the brainstem showed typical vascular enhancement. GFAP-A lacks specificity in clinical and MRI scans. When enhancement reveals paraventricular “vascular-like enhancement” or central spinal cord tubular enhancement, it is important to consider the possibility of this disease. |
format | Online Article Text |
id | pubmed-9114157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91141572022-05-19 MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() Ma, Wenhui Huang, Cong Yang, Lu Luo, Junde Radiol Case Rep Case Report Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) is a new type of autoimmune astrocytopathy first defined in 2016. Lack of clinical understanding, often misdiagnosed as optic neuromyelitis or multiple sclerosis. We report the clinical and MRI findings of an elderly patient with autoimmune glial fibrillary acidic protein astrocytopathy. With intractable vomiting as the first symptom, the brainstem showed typical vascular enhancement. GFAP-A lacks specificity in clinical and MRI scans. When enhancement reveals paraventricular “vascular-like enhancement” or central spinal cord tubular enhancement, it is important to consider the possibility of this disease. Elsevier 2022-05-12 /pmc/articles/PMC9114157/ /pubmed/35601378 http://dx.doi.org/10.1016/j.radcr.2022.04.032 Text en © 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Ma, Wenhui Huang, Cong Yang, Lu Luo, Junde MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() |
title | MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() |
title_full | MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() |
title_fullStr | MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() |
title_full_unstemmed | MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() |
title_short | MRI findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: Case report() |
title_sort | mri findings of autoimmune glial fibrillary acidic protein astrocytopathy involving infratentorial: case report() |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114157/ https://www.ncbi.nlm.nih.gov/pubmed/35601378 http://dx.doi.org/10.1016/j.radcr.2022.04.032 |
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