Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear

The loss of inner ear hair cells causes permanent hearing and balance deficits in humans and other mammals, but non-mammals recover after supporting cells (SCs) divide and replace hair cells. The proliferative capacity of mammalian SCs declines as exceptionally thick circumferential F-actin bands de...

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Detalles Bibliográficos
Autores principales: Rudolf, Mark A., Andreeva, Anna, Kim, Christina E., DeNovio, Anthony C.-J., Koshar, Antoan N., Baker, Wendy, Cartagena-Rivera, Alexander X., Corwin, Jeffrey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114303/
https://www.ncbi.nlm.nih.gov/pubmed/35602553
http://dx.doi.org/10.3389/fncel.2022.859882

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