Nucleotide-amino acid π-stacking interactions initiate photo cross-linking in RNA-protein complexes

Photo-induced cross-linking is a mainstay technique to characterize RNA-protein interactions. However, UV-induced cross-linking between RNA and proteins at “zero-distance” is poorly understood. Here, we investigate cross-linking of the RBFOX alternative splicing factor with its hepta-ribonucleotide...

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Detalles Bibliográficos
Autores principales: Knörlein, Anna, Sarnowski, Chris P., de Vries, Tebbe, Stoltz, Moritz, Götze, Michael, Aebersold, Ruedi, Allain, Frédéric H.-T., Leitner, Alexander, Hall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114321/
https://www.ncbi.nlm.nih.gov/pubmed/35581222
http://dx.doi.org/10.1038/s41467-022-30284-w

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