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27-Hydroxycholesterol induces expression of zonula occludens-1 in monocytic cells via multiple kinases pathways

Zonula occludens (ZO)-1, a tight-junction protein (TJP), is expressed in dendritic cells (DCs) but not in monocytes, and 27-hydroxycholesterol (27OHChol) drives the differentiation of monocytes into DCs. Because the effects of 27OHChol on ZO-1 are not yet clearly defined, we investigated whether 27O...

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Detalles Bibliográficos
Autores principales: Cho, Hyok-rae, Kim, Bo-Young, Kim, Koanhoi, Lee, Dongjun, Eo, Seong-Kug, Son, Yonghae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114403/
https://www.ncbi.nlm.nih.gov/pubmed/35581378
http://dx.doi.org/10.1038/s41598-022-12416-w