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Network Pharmacology-Based Prediction and Verification of Ginsenoside Rh2-Induced Apoptosis of A549 Cells via the PI3K/Akt Pathway

Ginsenoside Rh2 (G-Rh2), a rare protopanaxadiol (PPD)-type triterpene saponin, from Panax ginseng has anti-proliferation, anti-invasion, and anti-metastatic activity. However, the mechanisms by which G-Rh2 induces apoptosis of lung cancer cells are unclear. In the present work, a G-Rh2 target-lung c...

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Detalles Bibliográficos
Autores principales: Song, Chao, Yuan, Yue, Zhou, Jing, He, Ziliang, Hu, Yeye, Xie, Yuan, Liu, Nan, Wu, Lei, Zhang, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114502/
https://www.ncbi.nlm.nih.gov/pubmed/35600856
http://dx.doi.org/10.3389/fphar.2022.878937