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Heterozygous SOD2 deletion selectively impairs SERCA function in the soleus of female mice

The sarco(endo)plasmic reticulum Ca(2+) ATPase (SERCA) restores intracellular Ca(2+) ([Ca(2+)](i)) to resting levels after muscle contraction, ultimately eliciting relaxation. SERCA pumps are highly susceptible to tyrosine (T)‐nitration, impairing their ability to take up Ca(2+) resulting in reduced...

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Detalles Bibliográficos
Autores principales:	Braun, Jessica L., Messner, Holt N., Cleverdon, Riley E. G., Baranowski, Ryan W., Hamstra, Sophie I., Geromella, Mia S., Stuart, Jeffrey A., Fajardo, Val A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114654/ https://www.ncbi.nlm.nih.gov/pubmed/35581738 http://dx.doi.org/10.14814/phy2.15285

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