Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly

We describe an outbreak of delta variant SARS-CoV-2 on a psychogeriatric ward of elderly patients. Retrospectively collected data was analysed using Fisher's exact test to assess the association between patients’ vaccination status and infection rates, severity of disease and mortality. Vaccina...

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Autores principales: Malik, Adnan, Lehtola, Laura, Isosomppi, Sanna, Smura, Teemu, Saarenheimo, Jaana, Anttila, Veli-Jukka, Särelä, Eeva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114754/
https://www.ncbi.nlm.nih.gov/pubmed/35440347
http://dx.doi.org/10.1017/S0950268822000589
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author Malik, Adnan
Lehtola, Laura
Isosomppi, Sanna
Smura, Teemu
Saarenheimo, Jaana
Anttila, Veli-Jukka
Särelä, Eeva
author_facet Malik, Adnan
Lehtola, Laura
Isosomppi, Sanna
Smura, Teemu
Saarenheimo, Jaana
Anttila, Veli-Jukka
Särelä, Eeva
author_sort Malik, Adnan
collection PubMed
description We describe an outbreak of delta variant SARS-CoV-2 on a psychogeriatric ward of elderly patients. Retrospectively collected data was analysed using Fisher's exact test to assess the association between patients’ vaccination status and infection rates, severity of disease and mortality. Vaccination with two doses was shown to reduce severity of disease (5% vs. 75%, p < 0.001) and mortality (5% vs. 50%, p < 0.018) amongst an elderly inpatient population during an outbreak of delta variant SARS-CoV-2. Vaccination should be encouraged in elderly care institutions. Furthermore, adequate vaccination in elderly care institutions is an important consideration in current booster (third/fourth) dose schedules.
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spelling pubmed-91147542022-05-18 Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly Malik, Adnan Lehtola, Laura Isosomppi, Sanna Smura, Teemu Saarenheimo, Jaana Anttila, Veli-Jukka Särelä, Eeva Epidemiol Infect Original Paper We describe an outbreak of delta variant SARS-CoV-2 on a psychogeriatric ward of elderly patients. Retrospectively collected data was analysed using Fisher's exact test to assess the association between patients’ vaccination status and infection rates, severity of disease and mortality. Vaccination with two doses was shown to reduce severity of disease (5% vs. 75%, p < 0.001) and mortality (5% vs. 50%, p < 0.018) amongst an elderly inpatient population during an outbreak of delta variant SARS-CoV-2. Vaccination should be encouraged in elderly care institutions. Furthermore, adequate vaccination in elderly care institutions is an important consideration in current booster (third/fourth) dose schedules. Cambridge University Press 2022-04-20 /pmc/articles/PMC9114754/ /pubmed/35440347 http://dx.doi.org/10.1017/S0950268822000589 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Original Paper
Malik, Adnan
Lehtola, Laura
Isosomppi, Sanna
Smura, Teemu
Saarenheimo, Jaana
Anttila, Veli-Jukka
Särelä, Eeva
Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
title Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
title_full Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
title_fullStr Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
title_full_unstemmed Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
title_short Outbreak of delta variant SARS-CoV-2 virus on a psychogeriatric ward in Helsinki, Finland, August 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
title_sort outbreak of delta variant sars-cov-2 virus on a psychogeriatric ward in helsinki, finland, august 2021: two-dose vaccination reduces mortality and disease severity amongst the elderly
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114754/
https://www.ncbi.nlm.nih.gov/pubmed/35440347
http://dx.doi.org/10.1017/S0950268822000589
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