Cargando…
Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing
The Trachypithecus leucocephalus (white-headed langur) is a highly endangered, karst-endemic primate species, inhabiting the karst limestone forest in Guangxi, Southwest China. How white-headed langurs adapted to karst limestone and special dietary remains unclear. It is the first time to study the...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114771/ https://www.ncbi.nlm.nih.gov/pubmed/35601103 http://dx.doi.org/10.3389/fcimb.2022.872841 |
_version_ | 1784709853736861696 |
---|---|
author | Que, Tengcheng Pang, Xianwu Huang, Hongli Chen, Panyu Wei, Yinfeng Hua, Yiming Liao, Hongjun Wu, Jianbao Li, Shousheng Wu, Aiqiong He, Meihong Ruan, Xiangdong Hu, Yanling |
author_facet | Que, Tengcheng Pang, Xianwu Huang, Hongli Chen, Panyu Wei, Yinfeng Hua, Yiming Liao, Hongjun Wu, Jianbao Li, Shousheng Wu, Aiqiong He, Meihong Ruan, Xiangdong Hu, Yanling |
author_sort | Que, Tengcheng |
collection | PubMed |
description | The Trachypithecus leucocephalus (white-headed langur) is a highly endangered, karst-endemic primate species, inhabiting the karst limestone forest in Guangxi, Southwest China. How white-headed langurs adapted to karst limestone and special dietary remains unclear. It is the first time to study the correlation between the gut microbiome of primates and special dietary, and environment in Guangxi. In the study, 150 fecal samples are collected from nine primates in Guangxi, China. Metagenomic sequencing is used to analyze and compare the gut microbiome composition and diversity between white-headed langurs and other primates. Our results indicate that white-headed langurs has a higher diversity of microbiome than other primates, and the key microbiome are phylum Firmicutes, class Clostridia, family Lachnospiraceae, and genera Clostridiates and Ruminococcus, which are related to the digestion and degradation of cellulose. Ten genera are significantly more abundant in white-headed langurs and François’ langur than in other primates, most of which are high-temperature microbiome. Functional analysis reveals that energy synthesis-related pathways and sugar metabolism-related pathways are less abundant in white-headed langurs and François’ langur than in other primates. This phenomenon could be an adaptation mechanism of leaf-eating primates to low-energy diet. The gut microbiome of white-headed langurs is related to diet and karst limestone environment. This study could serve as a reference to design conservation breeding, manage conservation units, and determine conservation priorities. |
format | Online Article Text |
id | pubmed-9114771 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91147712022-05-19 Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing Que, Tengcheng Pang, Xianwu Huang, Hongli Chen, Panyu Wei, Yinfeng Hua, Yiming Liao, Hongjun Wu, Jianbao Li, Shousheng Wu, Aiqiong He, Meihong Ruan, Xiangdong Hu, Yanling Front Cell Infect Microbiol Cellular and Infection Microbiology The Trachypithecus leucocephalus (white-headed langur) is a highly endangered, karst-endemic primate species, inhabiting the karst limestone forest in Guangxi, Southwest China. How white-headed langurs adapted to karst limestone and special dietary remains unclear. It is the first time to study the correlation between the gut microbiome of primates and special dietary, and environment in Guangxi. In the study, 150 fecal samples are collected from nine primates in Guangxi, China. Metagenomic sequencing is used to analyze and compare the gut microbiome composition and diversity between white-headed langurs and other primates. Our results indicate that white-headed langurs has a higher diversity of microbiome than other primates, and the key microbiome are phylum Firmicutes, class Clostridia, family Lachnospiraceae, and genera Clostridiates and Ruminococcus, which are related to the digestion and degradation of cellulose. Ten genera are significantly more abundant in white-headed langurs and François’ langur than in other primates, most of which are high-temperature microbiome. Functional analysis reveals that energy synthesis-related pathways and sugar metabolism-related pathways are less abundant in white-headed langurs and François’ langur than in other primates. This phenomenon could be an adaptation mechanism of leaf-eating primates to low-energy diet. The gut microbiome of white-headed langurs is related to diet and karst limestone environment. This study could serve as a reference to design conservation breeding, manage conservation units, and determine conservation priorities. Frontiers Media S.A. 2022-05-04 /pmc/articles/PMC9114771/ /pubmed/35601103 http://dx.doi.org/10.3389/fcimb.2022.872841 Text en Copyright © 2022 Que, Pang, Huang, Chen, Wei, Hua, Liao, Wu, Li, Wu, He, Ruan and Hu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cellular and Infection Microbiology Que, Tengcheng Pang, Xianwu Huang, Hongli Chen, Panyu Wei, Yinfeng Hua, Yiming Liao, Hongjun Wu, Jianbao Li, Shousheng Wu, Aiqiong He, Meihong Ruan, Xiangdong Hu, Yanling Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing |
title | Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing |
title_full | Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing |
title_fullStr | Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing |
title_full_unstemmed | Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing |
title_short | Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing |
title_sort | comparative gut microbiome in trachypithecus leucocephalus and other primates in guangxi, china, based on metagenome sequencing |
topic | Cellular and Infection Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114771/ https://www.ncbi.nlm.nih.gov/pubmed/35601103 http://dx.doi.org/10.3389/fcimb.2022.872841 |
work_keys_str_mv | AT quetengcheng comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT pangxianwu comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT huanghongli comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT chenpanyu comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT weiyinfeng comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT huayiming comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT liaohongjun comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT wujianbao comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT lishousheng comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT wuaiqiong comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT hemeihong comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT ruanxiangdong comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing AT huyanling comparativegutmicrobiomeintrachypithecusleucocephalusandotherprimatesinguangxichinabasedonmetagenomesequencing |