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Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes

Type 1 diabetes (T1D) is an autoimmune disease that develops in the interplay between genetic and environmental factors. A majority of individuals who develop T1D have a HLA make up, that accounts for 50% of the genetic risk of disease. Besides these HLA haplotypes and the insulin region that import...

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Detalles Bibliográficos
Autores principales: Gootjes, Chelsea, Zwaginga, Jaap Jan, Roep, Bart O., Nikolic, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114814/
https://www.ncbi.nlm.nih.gov/pubmed/35603161
http://dx.doi.org/10.3389/fimmu.2022.886736