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The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL

BACKGROUND: CD19-directed chimeric antigen receptor T-cell therapy (CAR-T) represents a promising treatment modality for an increasing number of B-cell malignancies. However, prolonged cytopenias and infections substantially contribute to the toxicity burden of CAR-T. The recently developed CAR-HEMA...

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Detalles Bibliográficos
Autores principales:	Rejeski, Kai, Perez, Ariel, Iacoboni, Gloria, Penack, Olaf, Bücklein, Veit, Jentzsch, Liv, Mougiakakos, Dimitrios, Johnson, Grace, Arciola, Brian, Carpio, Cecilia, Blumenberg, Viktoria, Hoster, Eva, Bullinger, Lars, Locke, Frederick L, von Bergwelt-Baildon, Michael, Mackensen, Andreas, Bethge, Wolfgang, Barba, Pere, Jain, Michael D, Subklewe, Marion
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114843/ https://www.ncbi.nlm.nih.gov/pubmed/35580927 http://dx.doi.org/10.1136/jitc-2021-004475

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