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CAR-T Therapy for Pediatric High-Grade Gliomas: Peculiarities, Current Investigations and Future Strategies
High-Grade Gliomas (HGG) are among the deadliest malignant tumors of central nervous system (CNS) in pediatrics. Despite aggressive multimodal treatment - including surgical resection, radiotherapy and chemotherapy - long-term prognosis of patients remains dismal with a 5-year survival rate less tha...
Autores principales: | Antonucci, Laura, Canciani, Gabriele, Mastronuzzi, Angela, Carai, Andrea, Del Baldo, Giada, Del Bufalo, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115105/ https://www.ncbi.nlm.nih.gov/pubmed/35603195 http://dx.doi.org/10.3389/fimmu.2022.867154 |
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