Cargando…
Targeting SNORA38B attenuates tumorigenesis and sensitizes immune checkpoint blockade in non-small cell lung cancer by remodeling the tumor microenvironment via regulation of GAB2/AKT/mTOR signaling pathway
BACKGROUND: Non-coding RNAs (ncRNAs), including small nucleolar RNAs (snoRNAs), are widely involved in the physiological and pathological processes of human beings. While up to date, although considerable progress has been achieved in ncRNA-related pathogenesis of non-small cell lung cancer (NSCLC),...
Autores principales: | Zhuo, Yue, Li, Shujun, Hu, Wei, Zhang, Yu, Shi, Yufan, Zhang, Faxue, Zhang, Jian, Wang, Juan, Liao, Meijuan, Chen, Jiahao, Qian, Huiling, Li, Dejia, Sun, Chengcao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115109/ https://www.ncbi.nlm.nih.gov/pubmed/35577506 http://dx.doi.org/10.1136/jitc-2021-004113 |
Ejemplares similares
-
SNORA74B gene silencing inhibits gallbladder cancer cells by inducing PHLPP and suppressing Akt/mTOR signaling
por: Qin, Yiyu, et al.
Publicado: (2017) -
Clinical significance and prognostic value of small nucleolar RNA SNORA38 in breast cancer
por: Song, Jian, et al.
Publicado: (2022) -
Bacterial translocation and barrier dysfunction enhance colonic tumorigenesis
por: Zhang, Yongguo, et al.
Publicado: (2022) -
MCT4 blockade increases the efficacy of immune checkpoint blockade
por: Babl, Nathalie, et al.
Publicado: (2023) -
RARE-25. RETINAL ASTROCYTOMA mTOR INHIBITOR THERAPY IN TUBEROUS SCLEROSIS MOSAICISM
por: Evans, Naomi, et al.
Publicado: (2020)