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Retrospective analysis of metabolite patterns of clobazam and N-desmethylclobazam in human plasma by LC-MS/MS

INTRODUCTION: Clobazam is a benzodiazepine drug, used to treat Lennox-Gastaut syndrome in patients aged 2 years and older. OBJECTIVE: To support patient care, our laboratory developed a liquid chromatography tandem mass spectrometry (LC-MS/MS) method for the quantification of clobazam (CLB) and its...

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Detalles Bibliográficos
Autores principales:	Bajaj, Amol O., Ly, Diane, Johnson-Davis, Kamisha L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115114/ https://www.ncbi.nlm.nih.gov/pubmed/35602307 http://dx.doi.org/10.1016/j.jmsacl.2022.04.005

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