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Endothelial NOX4 Oxidase Negatively Regulates Inflammation and Improves Morbidity During Influenza A Virus Lung Infection in Mice

Endosomal NOX2 oxidase-dependent ROS production promotes influenza pathogenicity, but the role of NOX4 oxidase, which is highly expressed in the lung endothelium, is largely unknown. The aim of this study was to determine if endothelial NOX4 expression can influence viral pathology in vivo, using a...

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Detalles Bibliográficos
Autores principales:	Hendricks, Keshia S., To, Eunice E., Luong, Raymond, Liong, Felicia, Erlich, Jonathan R., Shah, Ajay M., Liong, Stella, O’Leary, John J., Brooks, Doug A., Vlahos, Ross, Selemidis, Stavros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115386/ https://www.ncbi.nlm.nih.gov/pubmed/35601109 http://dx.doi.org/10.3389/fcimb.2022.883448

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