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Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag

Obtaining up to date information on the number of UK COVID‐19 regional infections is hampered by the reporting lag in positive test results for people with COVID‐19 symptoms. In the UK, for ‘Pillar 2’ swab tests for those showing symptoms, it can take up to five days for results to be collated. We m...

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Detalles Bibliográficos
Autores principales: Jersakova, Radka, Lomax, James, Hetherington, James, Lehmann, Brieuc, Nicholson, George, Briers, Mark, Holmes, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115539/
https://www.ncbi.nlm.nih.gov/pubmed/35601481
http://dx.doi.org/10.1111/rssc.12557
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author Jersakova, Radka
Lomax, James
Hetherington, James
Lehmann, Brieuc
Nicholson, George
Briers, Mark
Holmes, Chris
author_facet Jersakova, Radka
Lomax, James
Hetherington, James
Lehmann, Brieuc
Nicholson, George
Briers, Mark
Holmes, Chris
author_sort Jersakova, Radka
collection PubMed
description Obtaining up to date information on the number of UK COVID‐19 regional infections is hampered by the reporting lag in positive test results for people with COVID‐19 symptoms. In the UK, for ‘Pillar 2’ swab tests for those showing symptoms, it can take up to five days for results to be collated. We make use of the stability of the under reporting process over time to motivate a statistical temporal model that infers the final total count given the partial count information as it arrives. We adopt a Bayesian approach that provides for subjective priors on parameters and a hierarchical structure for an underlying latent intensity process for the infection counts. This results in a smoothed time‐series representation nowcasting the expected number of daily counts of positive tests with uncertainty bands that can be used to aid decision making. Inference is performed using sequential Monte Carlo.
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spelling pubmed-91155392022-05-18 Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag Jersakova, Radka Lomax, James Hetherington, James Lehmann, Brieuc Nicholson, George Briers, Mark Holmes, Chris J R Stat Soc Ser C Appl Stat Original Articles Obtaining up to date information on the number of UK COVID‐19 regional infections is hampered by the reporting lag in positive test results for people with COVID‐19 symptoms. In the UK, for ‘Pillar 2’ swab tests for those showing symptoms, it can take up to five days for results to be collated. We make use of the stability of the under reporting process over time to motivate a statistical temporal model that infers the final total count given the partial count information as it arrives. We adopt a Bayesian approach that provides for subjective priors on parameters and a hierarchical structure for an underlying latent intensity process for the infection counts. This results in a smoothed time‐series representation nowcasting the expected number of daily counts of positive tests with uncertainty bands that can be used to aid decision making. Inference is performed using sequential Monte Carlo. John Wiley and Sons Inc. 2022-04-23 /pmc/articles/PMC9115539/ /pubmed/35601481 http://dx.doi.org/10.1111/rssc.12557 Text en © 2022 The Authors. Journal of the Royal Statistical Society: Series C (Applied Statistics) published by John Wiley & Sons Ltd on behalf of Royal Statistical Society. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Jersakova, Radka
Lomax, James
Hetherington, James
Lehmann, Brieuc
Nicholson, George
Briers, Mark
Holmes, Chris
Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag
title Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag
title_full Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag
title_fullStr Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag
title_full_unstemmed Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag
title_short Bayesian imputation of COVID‐19 positive test counts for nowcasting under reporting lag
title_sort bayesian imputation of covid‐19 positive test counts for nowcasting under reporting lag
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115539/
https://www.ncbi.nlm.nih.gov/pubmed/35601481
http://dx.doi.org/10.1111/rssc.12557
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