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Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities

Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their junctions and polarity while acquiring mesenchymal properties and invasive ability. Originally defined as an embryogenesis event, EMT has been recognized as a crucial process in tumor progression. During EMT, ce...

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Detalles Bibliográficos
Autores principales: Huang, Zhao, Zhang, Zhe, Zhou, Chengwei, Liu, Lin, Huang, Canhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115588/
https://www.ncbi.nlm.nih.gov/pubmed/35601657
http://dx.doi.org/10.1002/mco2.144