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Reduced tumor growth in EP2 knockout mice is related to signaling pathways favoring an increased local anti-tumor immunity in the tumor stroma

Inflammatory signaling through prostaglandin E2 receptor subtype 2 (EP2) is associated with malignant tumor growth in both experimental models and cancer patients. Thus, the absence of EP2 receptors in host tissues appears to reduce tumor growth and systemic inflammation by inducing major alteration...

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Detalles Bibliográficos
Autores principales:	Khan, Maria, Engström, Cecilia, Bourghardt Fagman, Johan, Smedh, Ulrika, Lundholm, Kent, Iresjö, Britt-Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115633/ https://www.ncbi.nlm.nih.gov/pubmed/35543149 http://dx.doi.org/10.3892/or.2022.8329

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