Filamin FLN-2 promotes MVB biogenesis by mediating vesicle docking on the actin cytoskeleton

Multivesicular bodies (MVBs) contain intralumenal vesicles that are delivered to lysosomes for degradation or released extracellularly for intercellular signaling. Here, we identified Caenorhabditis elegans filamin FLN-2 as a novel regulator of MVB biogenesis. FLN-2 co-localizes with V-ATPase subuni...

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Detalles Bibliográficos
Autores principales: Shi, Leiling, Jian, Youli, Li, Meijiao, Hao, Tianchao, Yang, Chonglin, Wang, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115679/
https://www.ncbi.nlm.nih.gov/pubmed/35575797
http://dx.doi.org/10.1083/jcb.202201020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115679/
https://www.ncbi.nlm.nih.gov/pubmed/35575797
http://dx.doi.org/10.1083/jcb.202201020

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