Cargando…

Pan-Cancer Study of SHC-Adaptor Protein 1 (SHC1) as a Diagnostic, Prognostic and Immunological Biomarker in Human Cancer

Background: Recent studies highlight the carcinogenesis role of SHC-adaptor protein 1 (SHC1) in cancer initiation, development, and progression. However, its aberrant expression, diagnostic and prognostic value remain unknown in a variety of tumors. Methods: The SHC1 expression profiles were analyze...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Jianlin, Gao, Gan, Li, Limin, Ding, Junping, Chen, Xianhua, Lei, Jianfei, Long, Haihua, Wu, Lihua, Long, Xin, He, Lian, Shen, Yongqi, Yang, Jinzhong, Lu, Yonggang, Sun, Yifan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115805/ https://www.ncbi.nlm.nih.gov/pubmed/35601500 http://dx.doi.org/10.3389/fgene.2022.817118

Ejemplares similares

The neuronal Shc adaptor in Alzheimer’s Disease
por: Triaca, Viviana, et al.
Publicado: (2018)

Insights into the Shc Family of Adaptor Proteins
por: Ahmed, Samrein B. M., et al.
Publicado: (2017)

Localization of phosphotyrosine adaptor protein ShcD/SHC4 in the adult rat central nervous system
por: Robeson, Hannah N., et al.
Publicado: (2019)

Bifurcation of Cell Migratory and Proliferative Signaling by the Adaptor Protein Shc
por: Collins, Lila R., et al.
Publicado: (1999)

The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor
por: Wills, Melanie K. B., et al.
Publicado: (2014)

ATHEROSCLEROSIS NEEDS SHC
por: Robinson, Richard
Publicado: (2008)

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
por: Ahn, Ryuhjin, et al.
Publicado: (2017)

The oxidative stress adaptor p66Shc is required for permanent embryo arrest in vitro
por: Favetta, Laura A, et al.
Publicado: (2007)

Modulation of Obesity and Insulin Resistance by the Redox Enzyme and Adaptor Protein p66(Shc)
por: Ciciliot, Stefano, et al.
Publicado: (2019)

Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells
por: Kakizawa, Sho, et al.
Publicado: (2020)

Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC
por: Onnis, Anna, et al.
Publicado: (2020)

Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells
por: Chen, Kuang-Den, et al.
Publicado: (2011)

Human SHC‐transforming protein 1 and its isoforms p66shc: A novel marker for prediabetes
por: Jelinek, Herbert F, et al.
Publicado: (2021)

SHC1 Promotes Lung Cancer Metastasis by Interacting with EGFR
por: Yang, Pan, et al.
Publicado: (2022)

The p66(Shc) Adaptor Protein Controls Oxidative Stress Response in Early Bovine Embryos
por: Betts, Dean H., et al.
Publicado: (2014)

Involvement of the neuronal phosphotyrosine signal adaptor N-Shc in kainic acid-induced epileptiform activity
por: Baba, Shiro, et al.
Publicado: (2016)

P66Shc (Shc1) Zebrafish Mutant Line as a Platform for Testing Decreased Reactive Oxygen Species in Pathology
por: Haslem, Landon, et al.
Publicado: (2022)

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1
por: Mehlitz, Adrian, et al.
Publicado: (2010)

Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1
por: Linossi, Edmond M., et al.
Publicado: (2013)

P66Shc signals to age
por: Trinei, Mirella, et al.
Publicado: (2009)

p66Shc in Cardiovascular Pathology
por: Haslem, Landon, et al.
Publicado: (2022)

Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia
por: Gillis, LC, et al.
Publicado: (2013)

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity
por: Shih, Hung-Ju, et al.
Publicado: (2012)

Brain-derived neurotrophic factor modulation of Kv1.3 channel is disregulated by adaptor proteins Grb10 and nShc
por: Colley, Beverly S, et al.
Publicado: (2009)

Sos-mediated activation of rac1 by p66shc
por: Khanday, Firdous A., et al.
Publicado: (2006)

P66SHC and Ageing: ROS and TOR?
por: Pani, Giovambattista
Publicado: (2010)

P66Shc and vascular endothelial function
por: Kumar, Santosh
Publicado: (2019)

p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy
por: Frackelton, A Raymond, et al.
Publicado: (2006)

Double p52Shc/p46Shc Rat Knockout Demonstrates Severe Gait Abnormalities Accompanied by Dilated Cardiomyopathy
por: Miller, Bradley, et al.
Publicado: (2021)

The p52 isoform of SHC1 is a key driver of breast cancer initiation
por: Wright, Kevin D., et al.
Publicado: (2019)

Temporal regulation of EGF signaling networks by the scaffold protein Shc1
por: Zheng, Yong, et al.
Publicado: (2013)

The Role of p66shc in Oxidative Stress and Apoptosis
por: Galimov, E.R.
Publicado: (2010)

p53 and aging: role of p66Shc
por: Migliaccio, Enrica, et al.
Publicado: (2013)

Clustering PPI data by combining FA and SHC method
por: Lei, Xiujuan, et al.
Publicado: (2015)

Sarcomatoid hepatocellular carcinoma (SHC): a case report
por: Yu, Yingying, et al.
Publicado: (2017)

P66Shc expression in diabetic rat retina
por: Zhao, Ming-Hui, et al.
Publicado: (2018)

Role of p66shc in skeletal muscle function
por: Granatiero, Veronica, et al.
Publicado: (2017)

Selective inhibition of protein kinase C β(2) attenuates the adaptor P66(Shc)-mediated intestinal ischemia–reperfusion injury
por: Chen, Z, et al.
Publicado: (2014)

The Shc Family Protein Adaptor, Rai, Negatively Regulates T Cell Antigen Receptor Signaling by Inhibiting ZAP-70 Recruitment and Activation
por: Ferro, Micol, et al.
Publicado: (2011)

DEPDC1B is a tumor promotor in development of bladder cancer through targeting SHC1
por: Lai, Chin-Hui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_81fvgol1odbksinpdoitneffno