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Efficacy and safety of Lenzumestrocel (Neuronata-R® inj.) in patients with amyotrophic lateral sclerosis (ALSUMMIT study): study protocol for a multicentre, randomized, double-blind, parallel-group, sham procedure-controlled, phase III trial

BACKGROUND: A single cycle (two repeated treatments) with intrathecal autologous bone marrow-derived mesenchymal stem cells (BM-MSCs, 26-day interval) showed safety and provided therapeutic benefit lasting 6 months in patients with ALS but did not demonstrate long-term efficacy. This phase III clini...

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Detalles Bibliográficos
Autores principales:	Nam, Jae-Yong, Lee, Tae Yong, Kim, Kwijoo, Chun, Sehwan, Kim, Min Sung, Shin, Jin-Hong, Sung, Jung-Joon, Kim, Byoung Joon, Kim, Byung-Jo, Oh, Ki-Wook, Kim, Kyung Suk, Kim, Seung Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115933/ https://www.ncbi.nlm.nih.gov/pubmed/35585556 http://dx.doi.org/10.1186/s13063-022-06327-4

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