Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival

BACKGROUND: Hepatocellular carcinoma (HCC) is a common primary liver cancer with poor overall survival. We hypothesized that there are HCC-associated cell-types that impact patient survival. METHODS: We combined liver single nucleus (snRNA-seq), single cell (scRNA-seq), and bulk RNA-sequencing (RNA-...

Descripción completa

Detalles Bibliográficos
Autores principales: Alvarez, Marcus, Benhammou, Jihane N., Darci-Maher, Nicholas, French, Samuel W., Han, Steven B., Sinsheimer, Janet S., Agopian, Vatche G., Pisegna, Joseph R., Pajukanta, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115949/
https://www.ncbi.nlm.nih.gov/pubmed/35581624
http://dx.doi.org/10.1186/s13073-022-01055-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115949/
https://www.ncbi.nlm.nih.gov/pubmed/35581624
http://dx.doi.org/10.1186/s13073-022-01055-5

Ejemplares similares