Radiogenomic analysis of primary breast cancer reveals [18F]-fluorodeoxglucose dynamic flux-constants are positively associated with immune pathways and outperform static uptake measures in associating with glucose metabolism

BACKGROUND: PET imaging of 18F-fluorodeoxygucose (FDG) is used widely for tumour staging and assessment of treatment response, but the biology associated with FDG uptake is still not fully elucidated. We therefore carried out gene set enrichment analyses (GSEA) of RNA sequencing data to find KEGG pa...

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Detalles Bibliográficos
Autores principales: Ralli, G. P., Carter, R. D., McGowan, D. R., Cheng, W.-C., Liu, D., Teoh, E. J., Patel, N., Gleeson, F., Harris, A. L., Lord, S. R., Buffa, F. M., Fenwick, J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115966/
https://www.ncbi.nlm.nih.gov/pubmed/35581637
http://dx.doi.org/10.1186/s13058-022-01529-9

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