Structural and functional specificity of H3K36 methylation

The methylation of histone H3 at lysine 36 (H3K36me) is essential for maintaining genomic stability. Indeed, this methylation mark is essential for proper transcription, recombination, and DNA damage response. Loss- and gain-of-function mutations in H3K36 methyltransferases are closely linked to hum...

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Detalles Bibliográficos
Autores principales: Lam, Ulysses Tsz Fung, Tan, Bryan Kok Yan, Poh, John Jia Xin, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116022/
https://www.ncbi.nlm.nih.gov/pubmed/35581654
http://dx.doi.org/10.1186/s13072-022-00446-7

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