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Diversity of Giant Viruses Infecting Vermamoeba vermiformis
The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field. Twelve years later, using another amoeba as a host, i.e., Vermamoeba vermiformis, novel isolates of giant viruses have been discovered. This am...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116030/ https://www.ncbi.nlm.nih.gov/pubmed/35602053 http://dx.doi.org/10.3389/fmicb.2022.808499 |
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author | Geballa-Koukoulas, Khalil La Scola, Bernard Blanc, Guillaume Andreani, Julien |
author_facet | Geballa-Koukoulas, Khalil La Scola, Bernard Blanc, Guillaume Andreani, Julien |
author_sort | Geballa-Koukoulas, Khalil |
collection | PubMed |
description | The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field. Twelve years later, using another amoeba as a host, i.e., Vermamoeba vermiformis, novel isolates of giant viruses have been discovered. This amoeba–virus relationship led scientists to study the evolution of giant viruses and explore the origins of eukaryotes. The purpose of this article is to review all the giant viruses that have been isolated from Vermamoeba vermiformis, compare their genomic features, and report the influence of these viruses on the cell cycle of their amoebal host. To date, viruses putatively belonging to eight different viral taxa have been described: 7 are lytic and 1 is non-lytic. The comparison of giant viruses infecting Vermamoeba vermiformis has suggested three homogenous groups according to their size, the replication time inside the host cell, and the number of encoding tRNAs. This approach is an attempt at determining the evolutionary origins and trajectories of the virus; therefore, more giant viruses infecting Vermamoeba must be discovered and studied to create a comprehensive knowledge on these intriguing biological entities. |
format | Online Article Text |
id | pubmed-9116030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91160302022-05-19 Diversity of Giant Viruses Infecting Vermamoeba vermiformis Geballa-Koukoulas, Khalil La Scola, Bernard Blanc, Guillaume Andreani, Julien Front Microbiol Microbiology The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field. Twelve years later, using another amoeba as a host, i.e., Vermamoeba vermiformis, novel isolates of giant viruses have been discovered. This amoeba–virus relationship led scientists to study the evolution of giant viruses and explore the origins of eukaryotes. The purpose of this article is to review all the giant viruses that have been isolated from Vermamoeba vermiformis, compare their genomic features, and report the influence of these viruses on the cell cycle of their amoebal host. To date, viruses putatively belonging to eight different viral taxa have been described: 7 are lytic and 1 is non-lytic. The comparison of giant viruses infecting Vermamoeba vermiformis has suggested three homogenous groups according to their size, the replication time inside the host cell, and the number of encoding tRNAs. This approach is an attempt at determining the evolutionary origins and trajectories of the virus; therefore, more giant viruses infecting Vermamoeba must be discovered and studied to create a comprehensive knowledge on these intriguing biological entities. Frontiers Media S.A. 2022-04-22 /pmc/articles/PMC9116030/ /pubmed/35602053 http://dx.doi.org/10.3389/fmicb.2022.808499 Text en Copyright © 2022 Geballa-Koukoulas, La Scola, Blanc and Andreani. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Geballa-Koukoulas, Khalil La Scola, Bernard Blanc, Guillaume Andreani, Julien Diversity of Giant Viruses Infecting Vermamoeba vermiformis |
title | Diversity of Giant Viruses Infecting Vermamoeba vermiformis |
title_full | Diversity of Giant Viruses Infecting Vermamoeba vermiformis |
title_fullStr | Diversity of Giant Viruses Infecting Vermamoeba vermiformis |
title_full_unstemmed | Diversity of Giant Viruses Infecting Vermamoeba vermiformis |
title_short | Diversity of Giant Viruses Infecting Vermamoeba vermiformis |
title_sort | diversity of giant viruses infecting vermamoeba vermiformis |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116030/ https://www.ncbi.nlm.nih.gov/pubmed/35602053 http://dx.doi.org/10.3389/fmicb.2022.808499 |
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