Cargando…

Diversity of Giant Viruses Infecting Vermamoeba vermiformis

The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field. Twelve years later, using another amoeba as a host, i.e., Vermamoeba vermiformis, novel isolates of giant viruses have been discovered. This am...

Descripción completa

Detalles Bibliográficos
Autores principales: Geballa-Koukoulas, Khalil, La Scola, Bernard, Blanc, Guillaume, Andreani, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116030/
https://www.ncbi.nlm.nih.gov/pubmed/35602053
http://dx.doi.org/10.3389/fmicb.2022.808499
_version_ 1784710038425698304
author Geballa-Koukoulas, Khalil
La Scola, Bernard
Blanc, Guillaume
Andreani, Julien
author_facet Geballa-Koukoulas, Khalil
La Scola, Bernard
Blanc, Guillaume
Andreani, Julien
author_sort Geballa-Koukoulas, Khalil
collection PubMed
description The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field. Twelve years later, using another amoeba as a host, i.e., Vermamoeba vermiformis, novel isolates of giant viruses have been discovered. This amoeba–virus relationship led scientists to study the evolution of giant viruses and explore the origins of eukaryotes. The purpose of this article is to review all the giant viruses that have been isolated from Vermamoeba vermiformis, compare their genomic features, and report the influence of these viruses on the cell cycle of their amoebal host. To date, viruses putatively belonging to eight different viral taxa have been described: 7 are lytic and 1 is non-lytic. The comparison of giant viruses infecting Vermamoeba vermiformis has suggested three homogenous groups according to their size, the replication time inside the host cell, and the number of encoding tRNAs. This approach is an attempt at determining the evolutionary origins and trajectories of the virus; therefore, more giant viruses infecting Vermamoeba must be discovered and studied to create a comprehensive knowledge on these intriguing biological entities.
format Online
Article
Text
id pubmed-9116030
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-91160302022-05-19 Diversity of Giant Viruses Infecting Vermamoeba vermiformis Geballa-Koukoulas, Khalil La Scola, Bernard Blanc, Guillaume Andreani, Julien Front Microbiol Microbiology The discovery of Acanthamoeba polyphaga mimivirus in 2003 using the free-living amoeba Acanthamoeba polyphaga caused a paradigm shift in the virology field. Twelve years later, using another amoeba as a host, i.e., Vermamoeba vermiformis, novel isolates of giant viruses have been discovered. This amoeba–virus relationship led scientists to study the evolution of giant viruses and explore the origins of eukaryotes. The purpose of this article is to review all the giant viruses that have been isolated from Vermamoeba vermiformis, compare their genomic features, and report the influence of these viruses on the cell cycle of their amoebal host. To date, viruses putatively belonging to eight different viral taxa have been described: 7 are lytic and 1 is non-lytic. The comparison of giant viruses infecting Vermamoeba vermiformis has suggested three homogenous groups according to their size, the replication time inside the host cell, and the number of encoding tRNAs. This approach is an attempt at determining the evolutionary origins and trajectories of the virus; therefore, more giant viruses infecting Vermamoeba must be discovered and studied to create a comprehensive knowledge on these intriguing biological entities. Frontiers Media S.A. 2022-04-22 /pmc/articles/PMC9116030/ /pubmed/35602053 http://dx.doi.org/10.3389/fmicb.2022.808499 Text en Copyright © 2022 Geballa-Koukoulas, La Scola, Blanc and Andreani. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Geballa-Koukoulas, Khalil
La Scola, Bernard
Blanc, Guillaume
Andreani, Julien
Diversity of Giant Viruses Infecting Vermamoeba vermiformis
title Diversity of Giant Viruses Infecting Vermamoeba vermiformis
title_full Diversity of Giant Viruses Infecting Vermamoeba vermiformis
title_fullStr Diversity of Giant Viruses Infecting Vermamoeba vermiformis
title_full_unstemmed Diversity of Giant Viruses Infecting Vermamoeba vermiformis
title_short Diversity of Giant Viruses Infecting Vermamoeba vermiformis
title_sort diversity of giant viruses infecting vermamoeba vermiformis
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116030/
https://www.ncbi.nlm.nih.gov/pubmed/35602053
http://dx.doi.org/10.3389/fmicb.2022.808499
work_keys_str_mv AT geballakoukoulaskhalil diversityofgiantvirusesinfectingvermamoebavermiformis
AT lascolabernard diversityofgiantvirusesinfectingvermamoebavermiformis
AT blancguillaume diversityofgiantvirusesinfectingvermamoebavermiformis
AT andreanijulien diversityofgiantvirusesinfectingvermamoebavermiformis