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Optimal Detection of Latent Mycobacterium tuberculosis Infection by Combined Heparin-Binding Hemagglutinin (HBHA) and Early Secreted Antigenic Target 6 (ESAT-6) Whole-Blood Interferon Gamma Release Assays

Optimal detection of latent tuberculosis (TB) infection (LTBI) remains a challenge, although it is essential to reach the goal of TB elimination. Our objective was to develop and clinically evaluate a user-friendly, 24-h, whole-blood (WB) interferon gamma (IFN-γ) release assay (IGRA) improving the d...

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Detalles Bibliográficos
Autores principales: Dirix, V., Dauby, N., Hites, M., Watelet, E., Van Praet, A., Godefroid, A., Petit, E., Singh, M., Locht, C., Mascart, F., Corbière, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116186/
https://www.ncbi.nlm.nih.gov/pubmed/35430897
http://dx.doi.org/10.1128/jcm.02443-21

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