Computational methods, databases and tools for synthetic lethality prediction

Synthetic lethality (SL) occurs between two genes when the inactivation of either gene alone has no effect on cell survival but the inactivation of both genes results in cell death. SL-based therapy has become one of the most promising targeted cancer therapies in the last decade as PARP inhibitors...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhang, Qinglong, Han, Junshan, Zhao, Yanpeng, Zhao, Caiyun, Yan, Bowei, Dai, Chong, Wu, Lianlian, Wen, Yuqi, Zhang, Yixin, Leng, Dongjin, Wang, Zhongming, Yang, Xiaoxi, He, Song, Bo, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116379/
https://www.ncbi.nlm.nih.gov/pubmed/35352098
http://dx.doi.org/10.1093/bib/bbac106

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