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The ART of tumor immune escape

We recently identified the adenosine-5′-diphosphate (ADP)–ribosyltransferase-1 (ART1) as a novel immune checkpoint expressed by cancer cells. ART1 utilizes free nicotinamide adenine dinucleotide (NAD(+)) in the tumor microenvironment (TME) to mono-ADP-ribosylate (MARylate) the P2X7 receptor (P2X7R)...

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Detalles Bibliográficos
Autores principales:	Wennerberg, Erik, Mukherjee, Sumit, Sainz, Ricardo M., Stiles, Brendon M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Author’s View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116389/ https://www.ncbi.nlm.nih.gov/pubmed/35602287 http://dx.doi.org/10.1080/2162402X.2022.2076310

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