A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations

Basement membranes (BMs) are ubiquitous extracellular matrices whose composition remains elusive, limiting our understanding of BM regulation and function. By developing a bioinformatic and in vivo discovery pipeline, we define a network of 222 human proteins and their animal orthologs localized to...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayadev, Ranjay, Morais, Mychel R. P. T., Ellingford, Jamie M., Srinivasan, Sandhya, Naylor, Richard W., Lawless, Craig, Li, Anna S., Ingham, Jack F., Hastie, Eric, Chi, Qiuyi, Fresquet, Maryline, Koudis, Nikki-Maria, Thomas, Huw B., O’Keefe, Raymond T., Williams, Emily, Adamson, Antony, Stuart, Helen M., Banka, Siddharth, Smedley, Damian, Sherwood, David R., Lennon, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116610/
https://www.ncbi.nlm.nih.gov/pubmed/35584218
http://dx.doi.org/10.1126/sciadv.abn2265

Ejemplares similares

Ejemplares similares