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Distinct responses to rare codons in select Drosophila tissues

Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression. Here, we use codon-modified reporters to perform an organism-wide screen in Drosophila melanogaster for dis...

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Detalles Bibliográficos
Autores principales: Allen, Scott R, Stewart, Rebeccah K, Rogers, Michael, Ruiz, Ivan Jimenez, Cohen, Erez, Laederach, Alain, Counter, Christopher M, Sawyer, Jessica K, Fox, Donald T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116940/
https://www.ncbi.nlm.nih.gov/pubmed/35522036
http://dx.doi.org/10.7554/eLife.76893