Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway

BACKGROUND: Limb ischemia/reperfusion (I/R) injury, as a life-threatening syndrome, is commonly caused by skeletal muscle damage resulting from oxidative stress. Additionally, inflammation-induced pyroptosis and dysregulated autophagy are vital factors contributing to the aggravation of I/R injury....

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Detalles Bibliográficos
Autores principales: Sun, Huanhuan, Wang, Jueqiong, Bi, Wei, Zhang, Feng, Chi, Kui, Shi, Long, Yuan, Tao, Ma, Kai, Gao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117032/
https://www.ncbi.nlm.nih.gov/pubmed/35600947
http://dx.doi.org/10.1155/2022/4653864

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