Cargando…

A Prognosis Marker Dynein Cytoplasmic 1 Heavy Chain 1 Correlates with EMT and Immune Signature in Liver Hepatocellular Carcinoma by Bioinformatics and Experimental Analysis

BACKGROUND: Liver hepatocellular carcinoma (LIHC) has had a continuous increase in incidence and mortality rates over the last 40 years. Dynein Cytoplasmic 1 Heavy Chain 1 (DYNC1H1) is a protein coding gene which encodes the cytoplasmic dynein heavy chain family. This is the first investigation into...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yanhong, Han, Jiyu, Zhou, Haichao, Ai, Songtao, Wan, Daqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117040/ https://www.ncbi.nlm.nih.gov/pubmed/35601740 http://dx.doi.org/10.1155/2022/6304859

Ejemplares similares

Integrated Bioinformatics and Experimental Analysis Identified TRIM28 a Potential Prognostic Biomarker and Correlated with Immune Infiltrates in Liver Hepatocellular Carcinoma
por: Han, Jiyu, et al.
Publicado: (2022)

Cytoplasmic dynein heavy chain: the servant of many masters
por: Schiavo, Giampietro, et al.
Publicado: (2013)

Expression of dynein, cytoplasmic 2, heavy chain 1 (DHC2) associated with glioblastoma cell resistance to temozolomide
por: Wang, Hai, et al.
Publicado: (2016)

Conditional Deletion of Cytoplasmic Dynein Heavy Chain in Postnatal Photoreceptors
por: Dahl, Tiffanie M., et al.
Publicado: (2021)

WDR92 is required for axonemal dynein heavy chain stability in cytoplasm
por: Patel-King, Ramila S., et al.
Publicado: (2019)

Effect of conditional deletion of cytoplasmic dynein heavy chain DYNC1H1 on postnatal photoreceptors
por: Dahl, Tiffanie M., et al.
Publicado: (2021)

The “8-kD” Cytoplasmic Dynein Light Chain Is Required for Nuclear Migration and for Dynein Heavy Chain Localization in Aspergillus nidulans
por: Beckwith, Susan M., et al.
Publicado: (1998)

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles
Publicado: (1996)

GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility
por: Gao, Feng J., et al.
Publicado: (2015)

Neuromuscular Junction Defects in Mice with Mutation of dynein heavy chain 1
por: Courchesne, Stephanie L., et al.
Publicado: (2011)

Cytoplasmic dynein nomenclature
por: Pfister, K. Kevin, et al.
Publicado: (2005)

Cytoplasmic Dynein Promotes HIV-1 Uncoating
por: Pawlica, Paulina, et al.
Publicado: (2014)

Interaction of the Zika virus with the cytoplasmic dynein-1
por: Zavala-Vargas, Dan Israel, et al.
Publicado: (2023)

Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid
Publicado: (1994)

Identification of the t Complex–encoded Cytoplasmic Dynein Light Chain Tctex1 in Inner Arm I1 Supports the Involvement of Flagellar Dyneins in Meiotic Drive
por: Harrison, Alistair, et al.
Publicado: (1998)

Axonemal dynein light chain-1 locates at the microtubule-binding domain of the γ heavy chain
por: Ichikawa, Muneyoshi, et al.
Publicado: (2015)

Apoptotic Cleavage of Cytoplasmic Dynein Intermediate Chain and P150(Glued)Stops Dynein-Dependent Membrane Motility
por: Lane, Jon D., et al.
Publicado: (2001)

Structural basis for cytoplasmic dynein-1 regulation by Lis1
por: Gillies, John P, et al.
Publicado: (2022)

Chymotryptic digestion of Tetrahymena ciliary dynein. II. Pathway of the degradation of 22S dynein heavy chains
Publicado: (1987)

Molecular Cloning of Dynein Heavy Chain and the Effect of Dynein Inhibition on the Testicular Function of Portunus trituberculatus
por: Xiang, Qiumeng, et al.
Publicado: (2021)

Cytoplasmic dynein1 intermediate-chain2 regulates cellular trafficking and physiopathological development in Magnaporthe oryzae
por: Lin, Lily, et al.
Publicado: (2023)

A Cytoplasmic Dynein Heavy Chain Is Required for Oscillatory Nuclear Movement of Meiotic Prophase and Efficient Meiotic Recombination in Fission Yeast
por: Yamamoto, Ayumu, et al.
Publicado: (1999)

Interactions of LC8 with N-Terminal Segments of the Intermediate Chain of Cytoplasmic Dynein
por: Nyarko, Afua, et al.
Publicado: (2003)

CD137 Regulates Bone Loss via the p53 Wnt/β-Catenin Signaling Pathways in Aged Mice
por: Han, Jiyu, et al.
Publicado: (2022)

The intraflagellar transport dynein complex of trypanosomes is made of a heterodimer of dynein heavy chains and of light and intermediate chains of distinct functions
por: Blisnick, Thierry, et al.
Publicado: (2014)

Neurodegenerative Mutation in Cytoplasmic Dynein Alters Its Organization and Dynein-Dynactin and Dynein-Kinesin Interactions
por: Deng, Wenhan, et al.
Publicado: (2010)

Lis1 promotes the formation of activated cytoplasmic dynein-1 complexes
por: Htet, Zaw Min, et al.
Publicado: (2020)

The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1
por: Twelvetrees, Alison E., et al.
Publicado: (2016)

Review: Cytoplasmic dynein motors in photoreceptors
por: Dahl, Tiffanie M., et al.
Publicado: (2021)

Conserved Roles for the Dynein Intermediate Chain and Ndel1 in Assembly and Activation of Dynein
por: Okada, Kyoko, et al.
Publicado: (2023)

Conserved roles for the dynein intermediate chain and Ndel1 in assembly and activation of dynein
por: Okada, Kyoko, et al.
Publicado: (2023)

ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms
por: Cho, Kyeong Jee, et al.
Publicado: (2018)

Dynein Modifiers in C. elegans: Light Chains Suppress Conditional Heavy Chain Mutants
por: O'Rourke, Sean M, et al.
Publicado: (2007)

Association between aberrant dynein cytoplasmic 1 light intermediate chain 1 expression levels, mucins and chemosensitivity in colorectal cancer
por: Chang, Chun-Chao, et al.
Publicado: (2020)

Isolated beta-heavy chain subunit of dynein translocates microtubules in vitro
Publicado: (1988)

A role for cytoplasmic dynein and LIS1 in directed cell movement
por: Dujardin, Denis L., et al.
Publicado: (2003)

RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs
por: McClintock, Mark A, et al.
Publicado: (2018)

MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment
por: Lee, Si-Hyung, et al.
Publicado: (2016)

Cortical Num1p Interacts with the Dynein Intermediate Chain Pac11p and Cytoplasmic Microtubules in Budding Yeast
por: Farkasovsky, Marian, et al.
Publicado: (2001)

Distinct roles of 1α and 1β heavy chains of the inner arm dynein I1 of Chlamydomonas flagella
por: Toba, Shiori, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_pvkpbtp96up80nk52rq3fu9gb1