Deubiquitinating enzymes and the proteasome regulate preferential sets of ubiquitin substrates

The ubiquitin-proteasome axis has been extensively explored at a system-wide level, but the impact of deubiquitinating enzymes (DUBs) on the ubiquitinome remains largely unknown. Here, we compare the contributions of the proteasome and DUBs on the global ubiquitinome, using UbiSite technology, inhib...

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Detalles Bibliográficos
Autores principales: Trulsson, Fredrik, Akimov, Vyacheslav, Robu, Mihaela, van Overbeek, Nila, Berrocal, David Aureliano Pérez, Shah, Rashmi G., Cox, Jürgen, Shah, Girish M., Blagoev, Blagoy, Vertegaal, Alfred C. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117253/
https://www.ncbi.nlm.nih.gov/pubmed/35585066
http://dx.doi.org/10.1038/s41467-022-30376-7

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