B cell-derived cfDNA after primary BNT162b2 mRNA vaccination anticipates memory B cells and SARS-CoV-2 neutralizing antibodies

BACKGROUND: Much remains unknown regarding the response of the immune system to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination. METHODS: We employed circulating cell-free DNA (cfDNA) to assess the turnover of specific immune cell types following administration of the Pfizer...

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Detalles Bibliográficos
Autores principales: Fox-Fisher, Ilana, Piyanzin, Sheina, Briller, Mayan, Oiknine-Djian, Esther, Alfi, Or, Ben-Ami, Roni, Peretz, Ayelet, Neiman, Daniel, Ochana, Bracha-Lea, Fridlich, Ori, Drawshy, Zeina, Klochendler, Agnes, Magenheim, Judith, Share, Danielle, Avrahami, Ran, Ribak, Yaarit, Talmon, Aviv, Rubin, Limor, Milman, Neta, Segev, Meital, Feldman, Erik, Tal, Yuval, Shen-Orr, Shai S., Glaser, Benjamin, Shemer, Ruth, Wolf, Dana, Dor, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Clinical and Translational Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117261/
https://www.ncbi.nlm.nih.gov/pubmed/35716665
http://dx.doi.org/10.1016/j.medj.2022.05.005

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